Book excerpt: Freedoms in material choice based on combinatorial design, different directions of process optimization, and computational tools are a significant advantage of additive manufacturing technology. The combination of additive and information technologies enables rapid prototyping and rapid manufacturing models on the design stage, thereby significantly accelerating the design cycle in mechanical engineering. Modern and high-demand powder bed fusion and directed energy deposition methods allow obtaining functional complex shapes and functionally graded structures. Until now, the experimental parametric analysis remains as the main method during AM optimization. Therefore, an additional goal of this book is to introduce readers to new modeling and material's optimization approaches in the rapidly changing world of additive manufacturing of high-performance metals and alloys.