Book excerpt: Promoting regional cooperation in the health sector is an operational priority of the Central Asia Regional Economic Cooperation (CAREC) Strategy 2030. This scoping study assesses the potential of CAREC to promote regional cooperation and integration in the health sector to mitigate risks and develop national health systems. The study specifically reviews the burden of communicable and noncommunicable diseases and their risk factors, along with the progress and challenges in health systems development in the CAREC region. Based on the assessment, the study recommends strengthening regional health security; developing health systems through regional cooperation; and improving health services for migrants, mobile populations, and border communities.