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Too often in biostatistical research and clinical trials, a knowledge gap exists between developed statistical methods and the applications of these methods. Fi

Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and

The world is awash in data. This volume of data will continue to increase. In the pharmaceutical industry, much of this data explosion has happened around bioma

Randomized clinical trials are the primary tool for evaluating new medical interventions. Randomization provides for a fair comparison between treatment and con

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical develo