Book excerpt: Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing prevalence and incidence in the last two decades. This book, edited by two experienced surgeons and a clinical psychologist in cooperation with numerous worldwide leading experts, presents clinically relevant information for gastroenterologists, internists, surgeons, residents and also nurses, who frequently care for GERD patients. Focusing on different treatment concepts – medical, endoscopic as well as surgical – the chapters include the basics of symptomatology and epidemiology, pathophysiology, GERD among different age groups, complications and its treatment, hiatal hernia or H. pylori and GERD, NERD and functional heartburn, diagnostic procedures and also presurgical examination. In addition, the patient's perspectives of disease, diagnostics and treatment are included, the same as economic aspects of GERD, and the impact of disease on quality of life or patient-reported outcomes after treatment.