Book excerpt: Annotation Interventional cardiologists, general cardiologists, endocrinologists, diabetologists The World Health Organization has projected that the prevalence of diabetes will double over the next 22 years - from a current figure of 150 million to an estimated 300 million people by the year 2025. The health-care burden of diabetes is enormous, and effective strategies to combat the explosive rise in the global incidence and prevalence of diabetes are urgently needed. Furthermore, diabetic patients have a considerable risk for cardiovascular disease, with up to 80% of deaths in individuals with diabetes attributable to microvascular or macrovascular complications. This book provides a concise overview of the present state of the art relating to the impact of diabetes mellitus on cardiovascular disease and to emerging treatment strategies that are beginning to impact on the management of the cardiovascular complications of this debilitating condition.