Book excerpt: This book is the research report of the 'Construction of Theory and Formation Mechanism of Total Innovation Management (TIM)' (Program No. 70372018), a program funded by the National Natural Science Foundation of China. This program aims to discuss and analyze, under the general trend of indigenous innovation, how enterprises construct indigenous innovation capability through total innovation management and to offer enterprises theoretical foundations and practical guidance to develop themselves towards indigenous innovation.The research results are not only the results of a three-year long research but also the reflection of the accumulated experiences of our research center in the field of technology innovation for nearly 40 years. In the field of technology innovation, we have experienced three distinct phases, namely: secondary innovation, portfolio innovation and total innovation.Total innovation is the main characteristic of an innovation-based enterprise. Creating an innovation-oriented enterprise by constructing a total innovation system is the approach that successful foreign enterprises use to move towards excellence and also the only way that Chinese enterprises have to take to become innovation-oriented enterprises that leapfrog in development.