Book excerpt: Competition for research funds in epidemiology, preventive medicine and biostatistics is highly competitive and at the same time, the grant application and review process at such agencies at the National Institutes of Health (NIH) has undergone substantial revisions. Writing Grant Proposals in Epidemiology, Preventive Medicine, and Biostatistics, Second Edition targets effective grant proposal writing in this highly competitive and evolving environment. Covering all aspects of the proposal writing process, the updated second edition: •Includes new chapters on Fellowship Grants and Career Development Awards designed for graduate students, postdoctoral fellows, and early-career faculty •Provides strategies to highlight the “overall impact” of the grant, one of the most important aspects determining NIH funding in a new chapter on Significance and Innovation •Provides step-by-step guidelines for grant structure and style alongside broader strategies for developing a research funding portfolio •Explains how to avoid common errors and pitfalls, supplying critical dos and don’ts that aid in writing solid grant proposals •Illustrates key concepts with extensive examples from successfully funded proposals Written by an established NIH reviewer with inside knowledge and an impressive track record of funding, Writing Grant Proposals in Epidemiology, Preventive Medicine, and Biostatistics, Second Edition is an essential cookbook of the appropriate ingredients needed to construct a winning grant proposal. The text is not only relevant for early-stage investigators including graduate students, medical students/residents, and postdoctoral fellows, but also valuable for more experienced faculty, clinicians, epidemiologists, and other health professionals who cannot seem to break the barrier to obtain NIH-funded research.