Book excerpt: The book covers advances in critical care pediatric nephrology, including care of sick children with acute kidney injury. The book contains detailed guidance on point of care ultrasound in children with acute kidney injury and use of biomarkers in critically sick children. This is an annual theme-based book with the current theme of 'point of care ultrasound in critical care pediatric nephrology and newer diagnostics in acute kidney injury'. This is the first book of the set of books to be published annually with a different theme related to critical care pediatric nephrology each year with the collaboration of the Pediatric Continous Renal Replacement Therapy (PCRRT) Foundation and International Collaboration of Nephrologists & Intensivists for Critical Care in Children (ICONIC). This annual updates book contains 20 chapters, written and edited by leading experts in pediatric intensive care, pediatric nephrology and nephrologists specializing in point of care ultrasound from across the globe. It includes top studies in the last few years in critical care pediatric nephrology on point of care ultrasound and diagnostics. Chapters cover scientifically updated information by international experts on each topic. It offers assistance to pediatricians, pediatric nephrologists, pediatric intensivists and residents.