Book excerpt: This book presents contributions to the 50th Annual Conference of the Operations Research Society of South Africa (ORSSA), which was jointly hosted with the African Federation of Operations Research Societies (AFROS) at North-West University in Potchefstroom, South Africa from 12 to 15 September, 2021. Focusing on innovative case studies and recent applications of Operations Research models and algorithms in African countries, each chapter highlights findings emerging from the countries in question and explains the lessons learned. As such, the book offers an up-to-date overview of Operations Research practices and developments in Africa. AFROS is a “not for profit” organization that aims to promote Operations Research in Africa. Its affairs are regulated by an Executive Committee consisting of representatives/alternates of all its member societies. The members of the Federation undertake to co-operate in the advancement of knowledge, interest and education in Operations Research by appropriate means, particularly the exchange of information, the holding of meetings and conferences, and the awarding of prizes.