Book excerpt: In this issue of Psychiatric Clinics, guest editors Drs. Stefan G. Hofmann, Jasper A.J. Smits, and Rianne A. de Kleine bring their considerable expertise to the topic of Cognitive Behavioral Therapy. Top experts in the field cover CBT for anxiety and depression in children and adolescents; cultural adaptions of CBT; psychedelic-assisted CBT; mindfulness-based CBT; scaling up CBT; and more. - Contains 13 relevant, practice-oriented topics including novel approaches towards studying mechanism, process based; CBT and digital; acceptance and commitment therapy; current status and future directions of CBT; and more. - Provides in-depth clinical reviews on cognitive behavioral therapy, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.