Book excerpt: The book constitutes the refereed proceedings of the 13th International Conference on Information Processing and Management of Uncertainty in Knowledge-Based Systems, IPMU 2010, held in Dortmund, Germany from June 28 - July 2, 2010. The 77 revised full papers were carefully reviewed and selected from 320 submissions and reflect the richness of research in the field of Computational Intelligence and represent developments on topics as: machine learning, data mining, pattern recognition, uncertainty handling, aggregation and fusion of information as well as logic and knowledge processing.