Book excerpt: Nowadays, philosophy and methodology of science appear as a combination of novelty and continuity. This blend is clear both in the general approaches to science (those thought of as any science) and in the specific perspectives on every science, either formal or empirical. There are new topics for philosophical reflection, such as key issues in philosophy of medicine and central problems raised by neuroscience. Thus, new contents have brought attention to aspects that previously went almost unnoticed. In addition, there are new angles for philosophical study, such as the repercussion of society on scientific activity (in aims, processes, and results). But the background of the main philosophical and methodological trends of the twentieth century is, in many ways, still in place.