Book excerpt: The purpose of this book is to extrapolate and bridge the sciences of pulmonary diseases with sciences that help medical professionals solve challenges of epidemics and pandemics such as COVID-19 and SARS-COV-2. You will find in the text information that will give credence to achieve goals and therapies paralleling the highest levels of medical practice. Acute and chronic respiratory illnesses have now become acceptable as the most prominent of diseases in the world, and henceforth as predicted, the trifecta of illnesses that are inherently increasing rapidly. However, on another cascade of health conditions, there have been major advances in our understanding of respiratory diseases and significant improvement in their management, particularly with the early and more widespread use of PPE (Personal Protective Equipment)[ Leading Health Research Institute] and respiratory ventilators. Yet, despite effective therapy for respiratory diseases, there is a pressing need for new and more specific therapies that control respiratory diseases or even cure the underlying disease process.