Book excerpt: This book discusses the question of how a regional economy can develop under the influence of an ageing and declining population, and how regional development policies can help make labor markets more resilient and more inclusive. As the greatest impacts of demographic change and policy and fiscal challenges can be observed at the local level, examples from European, North American and Asian regions are combined to present a comprehensive, global range of strategic solutions from different policy contexts. The book shows how institutions, organizations and communities can enhance their pathways for sustainable development through the intelligent management of their demographic transition, and offers a synthesis of valuable lessons and strategies.