Book excerpt: A finite element tool has been developed to design and investigate a multi-hull composite ship structure, and a hybrid hull of identical length and beam. Hybrid hull structure is assembled by Titanium alloy (Ti-6Al-4V) frame and sandwich composite panels. Wave loads and slamming loads acting on both hull structures have been calculated according to ABS rules at sea state 5 with a ship velocity of 40 knots. Comparisons of deformations and stresses between two sets of loadings demonstrate that slamming loads have more detrimental effects on ship structure. Deformation under slamming is almost one order higher than that caused by wave loads. Also, Titanium frame in hybrid hull significantly reduces both deformation and stresses when compared to composite hull due to enhancement of in plane strength and stiffness of the hull. A 73 m long hybrid hull has also been investigated under wave and slamming loads in time domain for dynamic analysis.