Book excerpt: This book provides practical knowledge on different aspects of information and knowledge management in businesses. For enterprises/businesses those intend to remain prosperous and prolific, it is critically important to share best practices, ensure efficient information flow across company, capturing shared knowledge centrally, and communicate compliance rules, i.e. managing competently information in general. It enables faster and better decisions by helping employees’ to build a strong expertise and by avoiding duplicated projects. Thus, the second volume of this series subline continues to explore different aspects of information and knowledge handling as well as doing business with information. We survey further the key aspects of managerial implications of the informational business. The novel methodologies and practices for the business information processing as well as application of mathematical models to the business analytics and efficient management are examined.