Book excerpt: This issue of Dental Clinics of North America focuses on Endodontics, and is edited by Dr. Mo Kang. Articles will include: Endodontic Microbiology and Pathobiology: Current State of Knowledge; Conventional Endodontic Therapies: Innovation in Biomechanics; Endodontic Retreatments: Non-surgical and Surgical Approaches; Pain Management in Endodontics: Opportunity for New Therapeutics; Pulpal Management of Immature Teeth: Use of New Biomaterials for Conservative Therapies; Innovation in Bioactive Restorative Materials; Topic in Regenerative Endodontics; Biological Molecules for the Regeneration of the Pulp-dentin Complex; Cell Homing Approach in Endodontic Regeneration; Stem Cell Therapies for Oral and Systemic Diseases; Endodontic Treatment Outcomes, and more!