Book excerpt: In this issue, guest editors bring their considerable expertise to this important topic. - Contains 14 practice-oriented topics including current topics in medical colic; complications and impact on outcome; what is the microbiota and what is its role in colic?; repeat laparotomy; ultrasonographic evaluation; and more. - Provides in-depth clinical reviews of equine colic, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.