Book excerpt: Evidence-based Nephrology provides students of nephrology and practicing clinicians with a convenient single source of clinical evidence that has been passed through an evidence-based filter. This fully revised second edition incorporates substantial new available data, updated methods of research synthesis, and a renewed focus on consumer engagement in the evaluation and management kidney disease. This updated textbook includes twenty new chapters and three new sections, covering supportive care and patient-centered care and outcomes. In addition, every chapter that was in the first edition has been extensively updated. This new edition covers epidemiology, acute kidney injury, primary diseases of the kidney, secondary diseases of the kidney, chronic kidney disease and complications, hemodialysis, chronic kidney disease stage 5, peritoneal dialysis, supportive care, transplantation, electrolytes and acid-base disorders, and patient centered care and outcomes for both adult and for pediatric patients. Boasting a new co-editor along with several new chapter authors and section editors, Evidence-based Nephrology is now an even better evidence-based nephrology tool, where each chapter provides a clear foundation of the topic that is supported by the best current evidence. This new edition includes broader coverage of the available evidence and addresses crucial clinical questions regarding the treatment and care of people with all stages of chronic kidney disease, including people undergoing any form of dialysis (hemodialysis or peritoneal dialysis), those requiring kidney transplantation and pediatric patients. Evidence-based Nephrology, Second Edition, is a core resource for the evidence-based nephrology practitioner who is otherwise limited by time constraints from researching every question that may arise daily in the care of their patients.