Book excerpt: Post COVID-19 pandemic, researchers have been evaluating the healthcare system for improvements that can be made. Understanding global healthcare systems’ operations is essential to preventative measures to be taken for the next global health crisis. A key part to bettering healthcare is the implementation of information management and One Health. The Handbook of Research on Essential Information Approaches to Aiding Global Health in the One Health Context evaluates the concepts in global health and the application of essential information management in healthcare organizational strategic contexts. This text promotes understanding in how evaluation health and information management are decisive for health planning, management, and implementation of the One Health concept. Covering topics like development partnerships, global health, and the nature of pandemics, this text is essential for health administrators, policymakers, government officials, public health officials, information systems experts, data scientists, analysts, health information science and global health scholars, researchers, practitioners, doctors, students, and academicians.