Book excerpt: In 2015 the Millennium Development Goals (MDGs) come to the end of their term, and a post-2015 agenda, comprising 17 Sustainable Development Goals (SDGs), takes their place. This WHO report looks back 15 years at the trends and positive forces during the MDG era and assesses the main challenges that will affect health in the coming 15 years. "Snapshots" on 34 different health topics outline trends, achievements made, reasons for success, challenges and strategic priorities for improving health in the different areas.--