Book excerpt: Now taught in a majority of medical schools nationwide, health systems science (HSS) prepares learners for the health systems of the future—an essential topic in modern health care. Health Systems Science Education, part of the American Medical Association’s MedEd Innovation Series, is a first-of-its-kind, instructor-focused field book that that equips educators to not just teach health systems science, but to know how to integrate and implement HSS comprehensively and effectively across the curriculum. This change management-oriented volume . . . Provides practical approaches and addresses common challenges to successfully implementing health systems science. Considers both clinical and classroom settings and discusses best practices, successful cases, and common frameworks implemented by early adopters of the third pillar of medical education. Contains clear lists of competencies. Covers both medical school (UME) and residency program (GME) implementation strategies. Offers a framework for creating an environment of continuous improvement—from pre-implementation to sustainability. One of the American Medical Association’s Change MedEd initiatives and innovations, written and edited by members of the Accelerating Change in Medical Education Consortium – a unique, innovative collaborative that allows for the sharing and dissemination of groundbreaking ideas and projects.