Book excerpt: Topics in detail to be covered are: Smarandache multi-spaces with applications to other sciences, such as those of algebraic multi-systems, multi-metric spaces; Smarandache geometries; Differential Geometry; Geometry on manifolds; Topological graphs; Algebraic graphs; Random graphs; Combinatorial maps; Graph and map enumeration; Combinatorial designs; Combinatorial enumeration; Low Dimensional Topology; Differential Topology; Topology of Manifolds; Geometrical aspects of Mathematical Physics and Relations with Manifold Topology; Applications of Smarandache multi-spaces to theoretical physics; Applications of Combinatorics to mathematics and theoretical physics.