Book excerpt: Manufacturing Systems represent an important field in Engineering Science and University Education. This volume develops key knowledge in Manufacturing Systems’ Design and Factory Operations right from the basics in Graph Theory, Systems Analysis, Petri nets, Simulation, Linear Programming, Queuing und Topology. These fundamentals enable to directly demonstrate current implementations of Processes and Factory Designs with a strong focus on work Organization and Information Flows. Moreover, advanced concept as Lean Manufacturing, Fractal Company or Cloud Manufacturing seamlessly fit into the presented structural set up. Methods for Greenfield planning, Master Plans, Layouts, and global manufacturing Site Decisions are discussed as well as all fundamentals around Enterprise Resource Planning, Manufacturing Execution, Scheduling and Supervisory Control and Data Acquisition. All subjects coalesce in novel ICT applications for Manufacturing, including Cyber Physical Production, Smart Units, Big Data, RFID and the Cloud. The book presents carefully pre-cogitated selections of key chapters from the wide fields of manufacturing systems and systems engineering. Master Students as well as Postgraduates find all important subjects and every key concept with easy access to all crucial recent developments in one volume. A number of authentic case examples from world class companies with novel aspects for Practitioners illustrate the matters. The book embraces more than two decades of practical experience from international projects as well as University lecturing on the addressed fields.