Book excerpt: Completely revised by new authors, this Fifth Edition presents 100 patient cases designed specifically to prepare students for clinical vignettes on the USMLE Step 1. Each case proceeds from chief complaint through diagnostic workup and treatment and includes buzzwords in history taking, physical examination, laboratory tests, imaging, and pathology. This edition's cases give greater emphasis to pathogenesis, epidemiology, differential diagnosis, management, and complications and include radiologic images, photographs, tables, and algorithms. A new two-page format encourages students to read the case presentation and formulate an initial diagnosis before turning the page for the answer. The book ends with twenty all-new board-format questions and answers.