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Type: BOOK - Published: 2001 - Publisher: Oxford University Press, USA
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This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, w
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Protein homeostasis, or “Proteostasis”, lies at the heart of human health and disease. From the folding of single polypeptide chains into functional protein
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Pages: 586
Pages: 586
Type: BOOK - Published: 1997-11-27 - Publisher: OUP Oxford
The precise shape of a protein is a crucial factor in its function. How do proteins become folded into the right conformation? Molecular chaperones and protein
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Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondri