Book excerpt: This book constitutes the refereed post-conference proceedings of the 7th International Conference on Next Generation Information Technologies and Systems, NGITS 2009, held in Haifa, Israel, in June 2009. The 14 revised full papers presented together with two keynote lectures and one invited paper were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on middleware and integration, modeling, healthcare/biomedical, service and information management, and applications.