Book excerpt: This document, with a focus on the built environment and health care facilities, intends to guide the audience in preparing for and responding to SARI pandemics caused by existing and novel pathogens. It provides technical guidance on designing, establishing, and managing health care facilities for severe acute respiratory infections (SARI), covering point of entry, treatment centers, entry to health system facilities, quarantine and community facilities, and home care and quarantine. Organized into three sections, it covers theoretical foundations, design principles, and implementation examples, including solution for new constructions, buildings repurposing, and temporary tent solutions. The technical representations of this publication are available in high resolution at: https://www.who.int/groups/techne