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The book focuses on protein allostery in drug discovery. Allosteric regulation, ʹthe second secret of lifeʹ, fine-tunes virtually most biological processes an

Although the concept of allosterism has been known for over half a century, its application in drug discovery has exploded in recent years. The emergence of nov

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biolog

A guide to applying the power of modern simulation tools to better drug design Biomolecular Simulations in Structure-based Drug Discovery offers an up-to-date a

Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered pro