Book excerpt: This volume contains the proceedings of the conference Recent Advances and New Directions in the Interplay of Noncommutative Algebra and Geometry, held from June 20–24, 2022, at the University of Washington, Seattle, in honor of S. Paul Smith's 65th birthday. The articles reflect the wide interests of Smith and provide researchers and graduate students with an indispensable overview of topics of current interest. Specific fields covered include: noncommutative algebraic geometry, representation theory, Hopf algebras and quantum groups, the elliptic algebras of Feigin and Odesskii, Calabi-Yau algebras, Artin-Schelter regular algebras, deformation theory, and Lie theory. In addition to original research contributions the volume includes an introductory essay reviewing Smith's research contributions in these fields, and several survey articles.