Book excerpt: The Middle Ages and the Renaissance were a period of scientific and literary reawakening. Scientific development and a renewed interest in classical science led to new discoveries, inventions, and technologies. Between 500 and 1600 A.D., scientific explorers rediscovered ancient Greek and Eastern knowledge, which led to an eruption of fresh ideas. This reference work describes more than 75 experiments, inventions, and discoveries of the period, as well as the scientists, physicians, and scholars responsible for them. Individuals such as Leonardo da Vinci, Marco Polo, and Galileo are included, along with entries on reconstructive surgery, Stonehenge, eyeglasses, the microscope, and the discovery of smallpox. Part of a unique series that ranges from ancient times to the 20th century, this exploration of scientific advancements during the Middle Ages and the Renaissance will be useful to high school and college students, teachers, and general readers seeking information about significant advances in scientific history.