Book excerpt: A specialist book for mental health professionals, sex therapists and educators to develop and improve their clinical work with trans clients with regards to their sexual relationships and sexuality. It provides an interdisciplinary exploration of the subject, and relates to both clinical practice and theory. Topics explored include the shifting of sexual orientation during or following gender transition; gender dysphoria and co-occurring autism spectrum disorder; negotiating issues of sexuality with partners during transition; eating disorders; and an exploration of the intersection of trans identities and disability. It uniquely touches on perspectives from the field of sex therapy, featuring chapter authors from disciplines including social work, marriage and family counseling, early childhood education, sex therapy, sex education, psychology, and women's studies.