Book excerpt: Statistical Geoinformatics for Human Environment Interface presents two paradigms for studying both space and interface with regard to human/environment: localization and multiple indicators. The first approach localizes thematic targets by treating space as a pattern of vicinities, with the pattern being a square grid and the placement of vicinities centrically referenced. The second approach explores human/environment interface as an abstraction through indicators, neutralizing the common conundrum of how to reconcile disparate spatial structures such as points, lines, and polygons. These paired paradigms enable: The capacity to cope with complexity Systematic surveillance Visualization and communication Preliminary prioritization Coupling of GIS and statistical software Avenues for automation Illustrating the interdisciplinary nature of geoinformatics, this book offers a novel approach to the spatial analysis of human influences and environmental resources. It includes practical strategies for statistical and spatial analysis.