Book excerpt: From Europe with "Industry 4.0" and from the US with "Smart Factory", the industrial model faces an unprecedented change. In this book we discover the 20 most important technologies that large companies are developing to continue dominating the market and thanks to which small and medium companies could increase their competitiveness and survive in a global market. This book, written in a language understandable to non-specialists, is intended to help as a navigation chart and compass, for all those who will face this fascinating challenge.IoT, AGV, RFID, RTLS, Additive Manufacturing, Collaborative Robots, PLM, Digital Twin, CPS, ... are some examples of the KETs (key enabling technologies) that we are going to show you.