Book excerpt: This book provides an interdisciplinary concept of digital working environments in industry 4.0 to enable the implementation of the digital twin of humans. Information and communication technology is penetrating all areas of daily life at a rapid pace in private and professional areas. These technologies enable companies to aggregate huge volumes of data. Collected personal data of employees creates the opportunity of a digital representation of the human being itself, that is conformant with the definition of a digital twin. These digital twins of humans include selected characteristics and behaviour of the humans, that are linked to models, information, and data. According to existing trend studies, the digital twin of humans is a technology that will have a significant impact on the economy, society, and people. It is important to consider the regulatory framework for the use of personal data and threats of misuse. This book will be of use to researchers and professionals in industry.