Book excerpt: This handbook is a practical and comprehensive guide to the diagnosis and management of osteoporosis. The book covers all aspects of osteoporosis, from pathophysiology to diagnostic tests and therapies, and includes actual case studies with teaching points. Separate chapters focus on vitamin D deficiency and workup and recognition of secondary causes of bone loss. Coverage of treatment includes tailoring therapy to individual patients, determining the success of therapy, what to do when therapy fails, and future therapeutic options. The authors review the latest evidence and provide annotated references so readers can examine the methodology, results, and conclusions of the studies.