Book excerpt: Adverse reactions to medicines continue to present a burden on healthcare, causing considerable morbidity and mortality. Aswell as knowing about the benefits of medicines, healthcare professionals need to understand the problem of adverse drugreactions and be aware of how they can be prevented and managed. This essential and practical guide has been extensively revised and updated to include three new chapters on adverse effectsof drugs in pregnancy, pharmacogenetics, and side effects and patients. Case studies are provided with each chapter.