Book excerpt: In this issue of Primary Care: Clinics in Office Practice, guest editors Drs. Andrew Lutzkanin and Kristen M. Lutzkanin bring their considerable expertise to the topic of Allergy and Immunology. Top experts in the field cover updated treatment strategies for common allergies encountered in primary care, including asthma, food and drug allergies, immunodeficiency, eosinophilic esophagitis, and more. Contains 12 practice-oriented topics including atopic dermatitis; drug allergy; acute and chronic urticaria and angioedema; venom hypersensitivity; contact dermatitis; and more. Provides in-depth clinical reviews on allergy and immunology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.