Book excerpt: Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question "How?" to also answering "Why?" - Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process. - Reviews neuromuscular physiology and the pathology of major diseases. - Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states. - Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves. - Features video clips of waveforms and of ultrasound images to illustrate key concepts. - An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine. - Any additional digital ancillary content may publish up to 6 weeks following the publication date.