Book excerpt: This book provides a single platform for beginners in systems engineering to start Arduino interface projects with MATLAB®. It covers the basics of the programming with Arduino and Arduino interfacing with MATLAB® (with and without the use or I/O packages) in 3 sections, respectively. Key features: -introduces readers to Arduino IDE, Proteus simulation modeling, Arduino interfaces with display devices, sensor interfaces (both digital and analog), actuators, MATLAB® GUIs, digital read/write systems with I/O interfaces and automation systems. -organized layout for a reader friendly experience -provides detailed circuit diagrams -provides relevant simulation modeling instructions This is an ideal book for engineering students and system designers for learning the basic programming and simulation of Arduino and MATLAB® based real time project prototypes.