Book excerpt: This book constitutes the post-conference proceedings of the 5th International Workshop on Attacks and Defenses for Internet-of-Things, ADIoT 2022, held in conjunction with ESORICS 2022, in Copenhagen, Denmark, in September 30, 2022, in hybrid mode. The 7 full papers and 3 short papers were carefully reviewed and selected from 18 submissions. This workshop focuses on IoT attacks and defenses and discusses either practical or theoretical solutions to identify IoT vulnerabilities and IoT security mechanisms.