Book excerpt: "When Charles Miller Fisher was born in 1913 there was little scientific knowledge about brain diseases and their treatment. Stroke, one of the most common and most feared among brain conditions, did an almost complete flip/flop during the 20th century. At the midpoint of the century, when Fisher began his career, there was little public or medical interest in stroke. By the end of the century stroke care and research was among the most intensely active areas within all of medicine. This book is the story of that change and of one physician, Dr. C. Miller Fisher, a main architect and driver of that change"--