Book excerpt: A comprehensive guide to the assessment, diagnosis, investigation and management of complex clinical scenarios in cardiovascular medicine. This book contains a series of challenging concepts in cardiovascular medicine covering all subspecialty areas including general cardiology, intervention, cardiac imaging, electrophysiology, heart failure and cardiomyopathies, cardiac devices, transplant medicine, epidemiology, heart disease in pregnancy and congenital heart disease. Each case provides an in-depth review of current practice, the application of national and international guidelines and a summary of evidence from the medical literature. Data sets, investigation results and cardiac imaging give the reader a 'real-life' sense of being in the outpatient clinic, emergency room, coronary care unit or cardiac catheterisation laboratory. Each case is punctuated by 'Clinical Tips', 'Learning Points' and 'Landmark Trial Summaries' to enhance the learning process alongside an 'Expert Commentary' written by internationally-renowned leaders in the field of cardiology.