Book excerpt: Clinical Prediction Rules: A Physical Therapy Reference Manual, is intended to be used for multiple musculoskeletal courses. It includes musculoskeletal clinical prediction rules organized by region, thus allowing for its repeated use during the upper and lower quarter as well as in the students spine coursework. Additionally this manual includes multiple medical screening prediction rules, making it appropriate for differential diagnosis and diagnostic imaging coursework. Perfect for entry-level physical therapy programs, this text is also suitable for post-professional physical therapy programs, especially those that include an orthopaedic residency or manual therapy fellowship program, and as a reference manual for students going out on their clinical rotations.