Book excerpt: From frontline experts on the topic—everything you need to know about COVID-19 and how it affects the heart COVID-19’s effect on the cardiovascular system continues to drive increases in morbidity and mortality. Building a solid understanding of the disease spectrum is critical for accurately diagnosing, treating, and managing patients with heart issues in the time of COVID. Written by a team of experts who worked on the frontlines in New York City throughout the worst of the pandemic, COVID-19 and the Heart: A Case-Based Pocket Guide is a one-of-a-kind resource for providing safe, effective care for COVID-19-related heart conditions. Designed for quick and easy learning and on-the-spot clinical decision making, this practical guide is organized into chapters based on genuine clinical cases and provides the best approach for each one. The authors highlight key points throughout the clinical content for easy review, and provide up-to-date information on clinical trials/vaccines, diagnostic and treatment algorithms, therapeutics, monitoring, and patient education. Ideal for healthcare workers actively engaged in the ongoing pandemic and students seeking to build their expertise, COVID-19 and the Heart is the go-to guide to making the right clinical judgments with respect to the cardiac manifestations of COVID-19. COVID-19 and the Heart starts with the physiology of COVID-related heart disease, and walks you through COVID’s effect on: ACS Valvular heart disease Arrythmia Pericardial disease Heart failure Shock Thromboembolism Hypertension