Book excerpt: We are today encountering numerous sustainable health concerns in relation to the existential threats caused by ecological and global changes. This book illustrates the ways in which health is being affected by anthropogenic human impacts on the environment, as well as climate change. It highlights synergistic, interventional approaches towards sustainable healthcare, together with innovative conceptual frameworks and models for facing the changing demands of our health needs under these current epidemiological and health transitions. It also sets out a vision of ecological principles to guide our professional directions with regards to sustainable health developments as legacy-based values across generations.