Book excerpt: This book describes a new design approach for energy-efficient, Domain-Specific Instruction set Processor (DSIP) architectures for the wireless baseband domain. The innovative techniques presented enable co-design of algorithms, architectures and technology, for efficient implementation of the most advanced technologies. To demonstrate the feasibility of the author’s design approach, case studies are included for crucial functionality of advanced wireless systems with increased computational performance, flexibility and reusability. Designers using this approach will benefit from reduced development/product costs and greater scalability to future process technology nodes.