Book excerpt: Now revised and expanded with over 50% new material, this definitive clinical reference is the text of choice for graduate-level courses in evidence-based psychotherapy. Foremost authorities describe the conceptual and scientific foundations of cognitive-behavioral therapy (CBT) and provide a framework for assessment and case formulation. Major approaches are reviewed in detail, including emotion-centered problem-solving therapy, rational emotive behavior therapy, cognitive therapy, schema therapy, mindfulness- and acceptance-based interventions, and dialectical behavior therapy (DBT). Applications to specific populations are discussed, including children and adolescents, couples, culturally diverse clients, and more. New to This Edition *Chapter on clinical assessment. *Chapter on DBT. *Chapters on transdiagnostic treatments, CBT-based prevention models, and improving dissemination and implementation. *Existing chapters extensively revised or rewritten to reflect important research and clinical advances.