Book excerpt: Handbook of Polytrauma Care and Rehabilitation will summarize the most frequent medical and psychological problems encountered by these patients, and offer a roadmap on how to initiate and follow through the continuum of care necessary to achieving positive outcomes. Individual chapters focus on the myriad problems and conditions that polytrauma patients present with, including traumatic injuries (TBI, concussion, SCI, amputation, PTSD, etc.) and other medical and psychological issues such as pain, depression, headache, insomnia, fatigue, alcohol and substance abuse, dizziness, light sensitivity, and work and family issues.