Book excerpt: Scaffold bone replacements are a safe and effective way to cure bone abnormalities, and porous scaffolds can be manufactured using additive manufacturing technology. When scaffolds are implanted in a damaged location, they quickly connect to the host tissue and integrate, stimulating bone production and development. The qualities of porous titanium must be matched to the properties of human bones (i.e., age, sex, and hormones). Using subtractive manufacturing, it is extremely difficult to create the complicated porous structure necessary for the desired characteristic. The Handbook of Research on Advanced Functional Materials for Orthopedic Applications highlights current research pertinent to the orthopedic applications of additive-produced scaffolds in order to consider the latest breakthroughs in the synthesis and multifunctional applications of scaffolds. Covering key topics such as tissue, additive manufacturing, and biomaterial, this major reference work is ideal for industry professionals, engineers, researchers, academicians, practitioners, scholars, instructors, and students.